CERO

Innovating 3D Culture

Stem cells – Spheroids – Organoids – Tissues

					Highlights
				
						Reduces cost, time spend and variations
Improved viability and maturation
Significantly reduced apoptosis & necrosis
Homogenous condition for homogeneous results
No shear forces and minimized gravity
Enabling pathogenic infection studies

Think in new dimensions – CERO is overcoming known limitations of static cultures.

Easy, ready-to-use protocols, standardizable workflows and autoadhesion of cells without any need for Carriers or Matrigel are just a few of the advantages.

As a result, CERO enables high yield expansion of pluripotent stem cells or long term cultivation of tissue for >20 days (Spheroids >80 or Organoids >180).

Cultivating hepatocyte spheroids in CERO considerably improves expansion, differentiation, maturation and hepatic virus infection compared to monolayer culture. Our research takes advantage from healthy cells even from long-term cultures in CERO. Moreover, we are now able to perform 3D long-term culture of human tissue specimen in CERO - a paradigm shift.

Prof. Dr. Heikenwälder, Chronic Inflammation and Cancer, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany

Upcoming CERO events

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Consumables

Name	Article number	Description	Quote	Order
CEROTubes	2800005	CEROTubes (48 units)	Quote	Order now

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Flyer

Application Note

Generation of HepaRG Spheroids in the CERO

Scientific Poster: "Establishment and validation of the 3D cultivation system“CERO” for hepatic spheroids to study viral hepatitis"

Scientific Poster: "Establishment and validation of the 3D cultivation system“CERO” for hepatic spheroids to study viral hepatitis", presented at the 2018 EMBL Symposium "Organoids: Modelling Organ Development and Disease in 3D Culture"

Protocol

Expansion Protocol Pluripotent Stem Cells (iPSC and ESC)

Protocol

Differentiation Protocol Organoids from Pluripotent Stem Cells

Get in touch

Britta Gerlach, PhD
Managing Director & Sales

britta.gerlach@ols-bio.ch Freecall (CH) 0800 666 454 +41 76 604 9829

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