Highlights
- Reduces cost, time spend and variations
- Improved viability and maturation
- Significantly reduced apoptosis & necrosis
- Homogenous condition for homogeneous results
- No shear forces and minimized gravity
- Enabling pathogenic infection studies
Think in new dimensions – CERO is overcoming known limitations of static cultures.
Easy, ready-to-use protocols, standardizable workflows and autoadhesion of cells without any need for Carriers or Matrigel are just a few of the advantages.
As a result, CERO enables high yield expansion of pluripotent stem cells or long term cultivation of tissue for >20 days (Spheroids >80 or Organoids >180).
Cultivating hepatocyte spheroids in CERO considerably improves expansion, differentiation, maturation and hepatic virus infection compared to monolayer culture. Our research takes advantage from healthy cells even from long-term cultures in CERO. Moreover, we are now able to perform 3D long-term culture of human tissue specimen in CERO - a paradigm shift.
Upcoming CERO events
Currently there are no upcoming events. Have a look at our overview of all events.
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Application Note
Generation of HepaRG Spheroids in the CERO
Scientific Poster: "Establishment and validation of the 3D cultivation system“CERO” for hepatic spheroids to study viral hepatitis"
Scientific Poster: "Establishment and validation of the 3D cultivation system“CERO” for hepatic spheroids to study viral hepatitis", presented at the 2018 EMBL Symposium "Organoids: Modelling Organ Development and Disease in 3D Culture"
Protocol
Expansion Protocol Pluripotent Stem Cells (iPSC and ESC)
Protocol
Differentiation Protocol Organoids from Pluripotent Stem Cells
Get in touch
Britta Gerlach, PhD
Sales
Your Partner in Cell Research
Laufenstrasse 90
4053 Basel, Switzerland