HiDef N-2 Neural Medium Supplement, LSS-501

HiDef N-2 is a defined formulation designed for the culture and growth of neurons, neural progenitor cells (NPCs), stem cells, and neuroblastoma (NB) cells, among other cell types, as well as differentiation of embryonic and induced pluripotent stem cells in neural and pancreatic lineages. HiDef N-2 is a combination of insulin (to stimulate glucose uptake), transferrin (to facilitate iron transport), sodium selenite (a potent antioxidant and common medium component), putrescine (for cell growth support), and progesterone (for promoting growth and neuronal differentiation and stimulation). N-2 has been historically shown to improve survival and expression of neuronal cells, including neurons in primary culture, and serves as an effective substitute for the N-1 Bottenstein formulation.

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