Organoid Development — Automated Imaging and Isolation
Accelerate growth and isolation of organoids.
Challenges using Traditional Organoid Cultures
Overlapping structures, requiring expensive multifocal imaging.
Heterogeneity in viability and phenotype.
Retrieval challenges due to viscous extracellular matrix.
Key Advantages CellRaft AIR® System
The CellRaft
AIR® System solves these issues with automated imaging and isolation for
high-quality 3D organoid culture.
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Grow & track hundreds of
organoids over time
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Perform on-array phenotypic
assessment
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Fully automate isolation of viable,
intact organoids
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Generate customized 96-well plates
for organoid-based assays (clonal propagation, drug screening, target
discovery)
Advanced Imaging & Analysis
- Z-stack imaging captures organoid structure in brightfield & fluorescence
- CellRaft Cytometry™ enables track-and-trace clonality verification
- AI-driven selection based on morphology, size, and fluorescence intensity
- Detailed phenotypic images are cataloged and easily exported for analysis
The intuitive software enables one-touch, full-array image scanning for seamless data capture.
Brightfield Imaging of Mouse Hepatic Organoids / EpCAM & Hoechst Imaging of Mouse Hepatic Organoids
CellRaft Cytometry™ identifies CellRafts containing 3D structures of interest, detecting organoids and verifying single-cell clonality, morphology, and growth rate. These critical data points ensure track-and-traceability for clonality confirmation. Selected organoids can be further evaluated based on diameter, circularity, and fluorescence intensity.
Perform phenotypic characterization with Raft Cytometry. / Identify and verify CellRafts containing 3D structures of interest and create sets of sub-populations for isolation
Gentle, Automated Isolation
The CellRaft
AIR® System’s 3D capabilities allow for
damage-free organoid retrieval, preserving viability for further growth and
research.
