CASY Vivo — Cell Counter and Viability Analyzer

The CASY Vivo Cell Counter & Analyzer supports Cell Science from simple fast in process controls control to high level of standardization of experiments in cell culture like CRISPR screens with mammalian cells, yeast and many species more.

Key Facts

Your Challenges in Cell Counting

Inaccurate cell counts and inconsistent results.

Time-consuming manual processes.

High costs for consumables.

Solved by Cell Counter and Analyzer

Great reproducibility from large stem cell aggregates to small yeast or even bacteria
Precise and reproducible analysis of cell volume and viability
Automated, dye-free counting for maximum accuracy
Faster analysis without complex sample preparation
Low running costs

"Already 20 years ago, I was searching for a machine which can count the cells in extremely short time. And I have found CASY as the machine which is very quick and also accurate. It is never broken."

Dr. Aziz Cayli, Founder and Chief Scientific Officer of Florabio

CASY - the Perfect Partner for Your Research

Elevating Cell Counting with Innovation, Accuracy, and Simplicity

Unmatched Precision and Reproducibility

Easy to use detection of Cell count, viability and volume in seconds.

No Sample Preparation

Dye-free, non-invasive counting saves time and preserves sample integrity.

Compatible with Various Cell Types

From stem cells and primary cells to bacteria and yeast, CASY adapts to your needs - ideal for toxicology, viability analysis, and more.

Save Costs and Time

CASY saves time and costs with minimal consumables and hands-on steps.

Regulatory Compliant

CASY supports GMP/GLP compliance with optional 21 CFR Part 11 compatibility - ideal for regulated research and QC labs.

User-Friendly Software

CASY’s intuitive software simplifies analysis and tracks cell growth, viability, and aggregation - with robust reporting for clear, reliable results.

CASY Vivo Cell Counter with CASYton and waste bottles

Trusted by Experts

"We study the regulation of cancer cell growth by signaling and metabolism. CASY is the ideal system for us to precisely measure proliferation and cell size of a wide range of cell lines. In this context, the new software makes instrument operation as well as data visualization and organization easy and convenient."

Dr. Wilhelm Palm • Head of the Junior Research Group Cell Signaling and Metabolism • German Cancer Research Center

"We use CASY cell counter for toxicological studies at a single animal level. The CASY cell counter proved to be an accurate and sensitive instrument for ecotoxicological applications allowing fast, simple and label-free measurements."

Prof. Dr. Konstantinos Grintzalis • School of Biotechnology • Dublin City University

"Cytotoxicity Assays using CASY enable us to perform fast, simple and reliable assessment of anti-cancer drug regimens and the subsequent chemosensitivity of carcinoma cell lines. A major advantage of CASY is that debris and dead cells can be masked in the analysis by a simle cell line speficfic setup and only viable cells and their aggregates are considered. However, as a complete cell status is recorded, also dead cells and debris data are available at any time."

Dr. J. Weinreich • Head of Experimental Oncology • University Hospital Tübingen

"We have successfully been using CASY for 10 years now. With CASY we are able to carry out reproducible cell culture experiments even when working with highly aggregated cells. CASY allows us to consider cell concentration and aggregation when seeding and harvesting cells, as both are measured by CASY. Measuring accurately cell number, the aggregation factor and the cell volume, gives us the opportunity to express analytical data as concentration per cell. Additionally, the molar amount of a substance within a cell can be calculated (used for example for metal uptake in μΜ)."

Prof. Dr. Julia Bornhorst • Professor for Food Chemistry with focus on Toxicology • University of Wuppertal

"We have been using CASY for the fast and reliable determination of cell concentrations and cell diameters of our cell cultures for 20 years now. We are still impressed by the high reproducibility of the measurements and the simple, intuitive operation of the device. The associated software offers great options for managing and displaying the measurement results graphically."

Dr. Heike Schwarz • Head of Cell Biology Department • DIARECT AG

"The CASY counter has been a key piece of equipment for the Oxford COVID-19 vaccine trial. We needed a reliable way to count cells from hundreds of blood samples on a daily basis. The CASY counter is a fast and accurate way of counting PBMCs. It is easy to use as it requires no sample preparation or staining, just add your sample to the CASYton buffer solution and it is ready to go! It is the gold standard of cell counting and we felt confident using it in our clinical trial due to its high reproducibility and accuracy."

Helen Sanders - Jenner Institute, COVID-19 Vaccine Trials

How it works

CASY: The Most Flexible Cell Counter

No need to search for the perfect cell counter - CASY does it all.

From cell lines and primary cells to PBMCs, stem cells, yeast, and bacteria, CASY delivers reliable results across all sample types. And with easily exchangeable capillaries, it’s ready to adapt as your workflows evolve.

Supports up to three interchangeable capillaries
Each capillary optimized for specific cell types
Quick and easy capillary switching within minutes
Flexible setup for diverse sample requirements

Learn more

Applications

"With CASY, we achieved more efficient and precise analysis of cell cultures."

- Prof. Dr. Julia Bornhorst, University of Wuppertal -

CASY Technology

How electrical current exclusion measures count, viability and volume without stains.

PBMCs

Counting peripheral blood mononuclear cells straight from the sample, without preparation.

Cytotoxicity

Assessing anti-cancer drug combinations and the chemosensitivity of carcinoma cell lines.

Algae Feeding-Daphnia

Track T-Cell Activation

Following T-cell activation through changes in cell volume, label-free.

iPSCs

Working with induced pluripotent stem cells, including aggregation and viability.

Algae and Protozoa

Counting algae and protozoa, from ecotoxicology studies to routine culture checks.

Bacteria

Measuring bacterial suspensions with the capillary matched to small cell sizes.

Erythrocytes & Platelets

Telling erythrocytes and platelets apart by volume, in one stain-free run.

Primary Cells

Handling sensitive primary cells without staining or extra sample preparation.

Fungi Spores

Counting fungal spores reproducibly, even in heterogeneous samples.

Pollen Counting

Counting and sizing pollen for aerobiology and quality control.

Trypanosoma & Leishmania

Counting parasitic protozoa quickly and without labelling.

Saccharomyces Cerevisiae

Monitoring yeast cultures: count, viability and budding within seconds.

Literature

CASY Cell Counter and Analyzer – More Than Counting: Explore the Latest Publications

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CASY Consumables

Scientists count on CASY for decades

CASY Cell Counter and Analyzers — *CASY Cell Counter through the years.*

FAQs

What is the CASY Cell Counter?

The CASY Cell Counter is an advanced cell analysis system that provides accurate cell counting, viability assessment, and volume measurement using label-free electrical current exclusion (ECE)-based technology.

How does the CASY Cell Counter work?

The system is based on electrical current exclusion (ECE) to analyze cells as they pass through a defined measurement pore, providing precise data on cell concentration, viability, and volume.

What types of cells can be analyzed with CASY?

CASY can analyze a wide range of cells, including mammalian cells, yeast, bacteria, algae, and other microorganisms, making it suitable for various research and industrial applications.

Is the CASY Cell Counter easy to use?

Yes! CASY features an intuitive interface, minimal sample preparation, and an user-friendly software for data analysis, making it ideal for both beginners and experienced researchers.

Can the CASY Cell Counter measure cell viability?

Yes, it differentiates between live and dead cells without staining by detecting differences in membrane integrity using electrical current exclusion (ECE).

How often does the CASY system need calibration?

CASY is calibrated for a lifetime, eliminating the need for regular quality control with calibration beads.

What maintenance is required?

CASY requires minimal maintenance, with a recommended weekly cleaning routine to ensure optimal accuracy.

Is training available for new users?

Yes, we provide online and in-person training sessions to ensure you get the most out of your CASY Cell Counter and Analyzer.

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CASY Vivo — Cell Counter and Viability Analyzer

Your Challenges in Cell Counting

Solved by Cell Counter and Analyzer