IL-1 beta human rec., 10 µg
Interleukin-1 beta (IL-1b) is produced by activated macrophages. IL-1b stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1b proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. IL-1b human recombinant produced in E. coli is a non-glycosylated, polypeptide chain containing 153 amino acids and having a molecular mass of 17,000 Dalton. The IL-1b is purified by proprietary chromatographic techniques.
Synonyms: Catabolin, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)
Storage Temperature: see datasheet