IL-10 human rec.
IL10 is a cytokine produced primarily by monocytes and to a lesser extent by TH2-lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation.
IL 10 inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells. It inhibits the formation of cytokines responsible for the Th1 answer thereby it promotes the survival, increase and the antibody production of B-lymphocytes.
It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway.
Synonyms: B-TCGF, CSIF, TGIF, IL-10, IL10A, MGC126450, MGC126451, Cytokine synthesis inhibitory factor
Storage Temperature: see datasheet
Interne Referenz: CB-2131000
Specifications
| Size | 10 µg or 2 µg |