By developing FBS Good we wanted to create a naturally defined serum with a sustained growth promoting property and a higher safety. FBS Good only contains serum of highest quality from defined countries as specified. It is not blended or enhanced by addition of growth factors or proteins.
FBS GOOD ADVANTAGES:
- Reproducible growth properties
- Suitable for a great variety of cells
- Continuous quality control

Storage Temperature: -20°C

Product Description
PAN-Biotech is known as a renowned producer of sera for cell culture. Our customers benefit from our years of experience and highly specialized products.
FROM COLLECTION TO THE FINAL PRODUCT:
The sample collection is taken from human, healthy donors in Europe, certified donations institutions.
Each donation is precisely tested regarding various biophysical parameters and viral infections and negative in the tests anti HIV 1/HIV 2, Hbs Ag, anti-HCV, HIV-1 Ag and/or HIV-1 NAT and Syphilis.
In each batch of human serum among others the osmolarity, pH, protein- and glucose concentration, and cell growth are measured and the sterility tested.
Human Sera from PAN-Biotech consist exclusively of human material. Human serum may be more suitable for the cultivation of human cells than FBS since serum and the cultured cells belong to the same species. Thus, the physiological and natural conditions
in vitro
are reproduced most similar to those
in vivo
. Human serum is particularly suitable for cell culture of human cells e.g. research in cell and immunotherapy, tissue engineering and other applications where the presence of animal derived components is unwanted.
PAN-Biotech offers three different categories of human serum: "Off the clot", Seraclot and converted human serum. Within these three categories it is possible to choose between a mixed groups pool or human serum AB.
SERACLOT:
Seraclot is a human serum, which is equal to the „off-the-clot“ serum in cell culture and in many cases exceeds its quality. An increased content of growth factors expands the possibilities in therapeutic cell culture. Seraclot is excellently suited for tissue engineering and cell differentiation. Seraclot is composed exclusively of human material.
HUMAN SERUM FROM PAN-BIOTECH:
Human serum is produced from human plasma by addition of calcium chloride. This results in clotting of the plasma. After the coagulation process the cellular and solid constituents of the serum are removed by centrifugation, the human serum is washed and concentrated by ultra-filtration and finally filtered through a combination of depth- and membrane- filters.
PAN-Biotech offers also converted human serum from donors with the blood group AB. Their blood does not contain anti-A nor anti-B antibodies, that could damage cultured cells and is therefore particularly suitable for immunological and hematopoietic studies.
CUSTOMER INFORMATION:
Human serum is a natural product. After the sterile filtration it is bottled and frozen as a clear solution. After thawing a slight blur may occur. This does not mean any loss of quality and the serum can be added to the medium without concerns.
Human serum is usually used in a concentration between 5% and 20%.
Cells cultured with FBS should be adapted step by step to the new serum. Initially, the cells should be cultivated for 4-6 days with a 10% serum mixture, consisting of 5% FBS and 5% human serum. Afterwards the final conversion to human serum can take place.

Storage Temperature: -20°C

PAN-Biotech is known as a renowned producer of sera for cell culture. Our customers benefit from our years of experience and highly specialized products.
FROM COLLECTION TO THE FINAL PRODUCT:
The sample collection is taken from human, healthy donors in Europe, certified donations institutions.
Each donation is precisely tested regarding various biophysical parameters and viral infections and negative in the tests anti HIV 1/HIV 2, Hbs Ag, anti-HCV, HIV-1 Ag and/or HIV-1 NAT and Syphilis.
In each batch of human serum among others the osmolarity, pH, protein- and glucose concentration, and cell growth are measured and the sterility tested.
Human Sera from PAN-Biotech consist exclusively of human material. Human serum may be more suitable for the cultivation of human cells than FBS since serum and the cultured cells belong to the same species. Thus, the physiological and natural conditions in vitro are reproduced most similar to those in vivo . Human serum is particularly suitable for cell culture of human cells e.g. research in cell and immunotherapy, tissue engineering and other applications where the presence of animal derived components is unwanted.
PAN-Biotech offers three different categories of human serum: "Off the clot", Seraclot and converted human serum. Within these three categories it is possible to choose between a mixed groups pool or human serum AB.
OFF-THE-CLOT SERUM:
Off-the-clot serum is prepared from human whole blood collected without anti-coagulant, allowed to clot at room temperature and then centrifuged to remove the clot. We provide single donor units as well as pooled off-the-clot serum. Off-the-clot serum is filtered through depth and membrane filters before filling.
HUMAN SERUM FROM PAN-BIOTECH:
Human serum is produced from human plasma by addition of calcium chloride. This results in clotting of the plasma. After the coagulation process the cellular and solid constituents of the serum are removed by centrifugation, the human serum is washed and concentrated by ultra-filtration and finally filtered through a combination of depth- and membrane- filters.
PAN-Biotech offers also converted human serum from donors with the blood group AB. Their blood does not contain anti-A nor anti-B antibodies, that could damage cultured cells and is therefore particularly suitable for immunological and hematopoietic studies.
CUSTOMER INFORMATION:
Human serum is a natural product. After the sterile filtration it is bottled and frozen as a clear solution. After thawing a slight blur may occur. This does not mean any loss of quality and the serum can be added to the medium without concerns.
Human serum is usually used in a concentration between 5% and 20%.
Cells cultured with FBS should be adapted step by step to the new serum. Initially, the cells should be cultivated for 4-6 days with a 10% serum mixture, consisting of 5% FBS and 5% human serum. Afterwards the final conversion to human serum can take place.

Storage Temperature: -20°C

Since 1988, PAN-Biotech is known as a renowned producer of sera for cell culture.
Our customers benefit from our years of experience and highly specialized products.
FROM COLLECTION TO THE FINAL PRODUCT:
The sample collection is taken from human, healthy donors in Europe, certified donations institutions.
Each donation is precisely tested regarding various biophysical parameters and viral infections and negative in the tests anti HIV 1/HIV 2, Hbs Ag, anti-HCV, HIV-1 Ag and/or HIV-1 NAT and Syphilis.
In each batch of human serum among others the osmolarity, pH, protein- and glucose concentration, and cell growth are measured and the sterility tested.
Human Sera from PAN-Biotech consist exclusively of human material. Human serum may be more suitable for the cultivation of human cells than FBS since serum and the cultured cells belong to the same species. Thus, the physiological and natural conditions in vitro are reproduced most similar to those in vivo . Human serum is particularly suitable for cell culture of human cells e.g. research in cell and immunotherapy, tissue engineering and other applications where the presence of animal derived components is unwanted.
PAN-Biotech offers three different categories of human serum: "Off the clot", Seraclot and converted human serum. Within these three categories it is possible to choose between a mixed groups pool or human serum AB.
HUMAN SERUM FROM PAN-BIOTECH:
Human serum is produced from human plasma by addition of calcium chloride. This results in clotting of the plasma. After the coagulation process the cellular and solid constituents of the serum are removed by centrifugation, the human serum is washed and concentrated by ultra-filtration and finally filtered through a combination of depth- and membrane- filters.
PAN-Biotech offers also converted human serum from donors with the blood group AB. Their blood does not contain anti-A nor anti-B antibodies, that could damage cultured cells and is therefore particularly suitable for immunological and hematopoietic studies.
CUSTOMER INFORMATION:
Human serum is a natural product. After the sterile filtration it is bottled and frozen as a clear solution. After thawing a slight blur may occur. This does not mean any loss of quality and the serum can be added to the medium without concerns.
Human serum is usually used in a concentration between 5% and 20%.
Cells cultured with FBS should be adapted step by step to the new serum. Initially, the cells should be cultivated for 4-6 days with a 10% serum mixture, consisting of 5% FBS and 5% human serum. Afterwards the final conversion to human serum can take place.

Storage Temperature: -20°C

Since 1988, PAN-Biotech is known as a renowned producer of sera for cell culture.
Our customers benefit from our years of experience and highly specialized products.
FROM COLLECTION TO THE FINAL PRODUCT:
The sample collection is taken from human, healthy donors in Europe, certified donations institutions.
Each donation is precisely tested regarding various biophysical parameters and viral infections and negative in the tests anti HIV 1/HIV 2, Hbs Ag, anti-HCV, HIV-1 Ag and/or HIV-1 NAT and Syphilis.
In each batch of human serum among others the osmolarity, pH, protein- and glucose concentration, and cell growth are measured and the sterility tested.
Human Sera from PAN-Biotech consist exclusively of human material. Human serum may be more suitable for the cultivation of human cells than FBS since serum and the cultured cells belong to the same species. Thus, the physiological and natural conditions in vitro are reproduced most similar to those in vivo. Human serum is particularly suitable for cell culture of human cells e.g. research in cell and immunotherapy, tissue engineering and other applications where the presence of animal derived components is unwanted.
PAN-Biotech offers three different categories of human serum: "Off the clot", Seraclot and converted human serum. Within these three categories it is possible to choose between a mixed groups pool or human serum AB.
OFF-THE-CLOT SERUM:
Off-the-clot serum is prepared from human whole blood collected without anti-coagulant, allowed to clot at room temperature and then centrifuged to remove the clot. We provide single donor units as well as pooled off-the-clot serum. Off-the-clot serum is filtered through depth and membrane filters before filling.
HUMAN SERUM FROM PAN-BIOTECH:
Human serum is produced from human plasma by addition of calcium chloride. This results in clotting of the plasma. After the coagulation process the cellular and solid constituents of the serum are removed by centrifugation, the human serum is washed and concentrated by ultra-filtration and finally filtered through a combination of depth- and membrane- filters.
PAN-Biotech offers also converted human serum from donors with the blood group AB. Their blood does not contain anti-A nor anti-B antibodies, that could damage cultured cells and is therefore particularly suitable for immunological and hematopoietic studies.
CUSTOMER INFORMATION:
Human serum is a natural product. After the sterile filtration it is bottled and frozen as a clear solution. After thawing a slight blur may occur. This does not mean any loss of quality and the serum can be added to the medium without concerns.
Human serum is usually used in a concentration between 5% and 20%.
Cells cultured with FBS should be adapted step by step to the new serum. Initially, the cells should be cultivated for 4-6 days with a 10% serum mixture, consisting of 5% FBS and 5% human serum. Afterwards the final conversion to human serum can take place.

Storage Temperature: -20°C

Since 1988, PAN-Biotech is known as a renowned producer of sera for cell culture.
Our customers benefit from our years of experience and highly specialized products.
FROM COLLECTION TO THE FINAL PRODUCT:
The sample collection is taken from human, healthy donors in Europe, certified donations institutions.
Each donation is precisely tested regarding various biophysical parameters and viral infections and negative in the tests anti HIV 1/HIV 2, Hbs Ag, anti-HCV, HIV-1 Ag and/or HIV-1 NAT and Syphilis.
In each batch of human serum among others the osmolarity, pH, protein- and glucose concentration, and cell growth are measured and the sterility tested.
Human Sera from PAN-Biotech consist exclusively of human material. Human serum may be more suitable for the cultivation of human cells than FBS since serum and the cultured cells belong to the same species. Thus, the physiological and natural conditions in vitro are reproduced most similar to those in vivo . Human serum is particularly suitable for cell culture of human cells e.g. research in cell and immunotherapy, tissue engineering and other applications where the presence of animal derived components is unwanted.
PAN-Biotech offers three different categories of human serum: "Off the clot", Seraclot and converted human serum. Within these three categories it is possible to choose between a mixed groups pool or human serum AB.
HUMAN SERUM FROM PAN-BIOTECH:
Human serum is produced from human plasma by addition of calcium chloride. This results in clotting of the plasma. After the coagulation process the cellular and solid constituents of the serum are removed by centrifugation, the human serum is washed and concentrated by ultra-filtration and finally filtered through a combination of depth- and membrane- filters.
PAN-Biotech offers also converted human serum from donors with the blood group AB. Their blood does not contain anti-A nor anti-B antibodies, that could damage cultured cells and is therefore particularly suitable for immunological and hematopoietic studies.
CUSTOMER INFORMATION:
Human serum is a natural product. After the sterile filtration it is bottled and frozen as a clear solution. After thawing a slight blur may occur. This does not mean any loss of quality and the serum can be added to the medium without concerns.
Human serum is usually used in a concentration between 5% and 20%.
Cells cultured with FBS should be adapted step by step to the new serum. Initially, the cells should be cultivated for 4-6 days with a 10% serum mixture, consisting of 5% FBS and 5% human serum. Afterwards the final conversion to human serum can take place.

Storage Temperature: -20°C

Various cell culture applications are suitable for other animal sera.
APPLICATION:
- Autologous cell culture systems
- Immuno histochemistry
- Immunoblotting
- Immunofluorescence
- Immunoprecipitation
TEST PARAMETER:
- pH
- Osmolality
- Endotoxin
- Total protein
- Hemoglobin
- Mycoplasma
- Sterility

Storage Temperature: -20°C

Various cell culture applications are suitable for other animal sera.
APPLICATION:
- Autologous cell culture systems
- Immuno histochemistry
- Immunoblotting
- Immunofluorescence
- Immunoprecipitation
TEST PARAMETER:
- pH
- Osmolality
- Endotoxin
- Total protein
- Hemoglobin
- Mycoplasma
- Sterility

Storage Temperature: -20°C

Panexin basic is a fully defined serum replacement for the cultivation of adherent and non-adherent cells under serum-free culture conditions or to significantly reduce the amount of serum in cell culture. It supports the growth of many cell types in an optimum manner without any extra handling compared to serum.
COMPOSITION:
Panexin basic contains purified proteins, lipids, salts, amino acids, trace elements, hormones and a 3-dimensional substrate release system in an optimized formulation. It contains no growth factors, undefined hydrolysates or peptones.
SUITABILITY:
Panexin basic is suitable for the cultivation of a variety of adherent and non-adherent cells under serum-free culture conditions. Further informations can be found in the datasheet.
SPECIAL ADVANTAGES:
Panexin basic is designed to replace or to reduce serum in the cell culture in a very simple manner. In most cases there is no need to change the basal medium. As Panexin basic is fully defined and contains no peptones or hydrolysates, lot testing is no more necessary. It also allows high reproducibility and a simplified downstream process. Panexin basic contains no growth factors and enables defined proliferation and differentiation of stem cells. Characterization studies of growth factors will obtain more reproducible and clearer results. Panexin basic is also useful to develop sensitive cell-based in vitro tests and coculture procedures.

Storage Temperature: -20°C

PowerStem MSC1 is an easy to use xeno-free medium for in vivo proliferation of human mesenchymal stem cells (hMSC). PowerStem MSC1 supports long-term growth of MSC and preserves their multi-lineage potential. In addition, MSC cultured in PowerStem MSC1 expands faster and shows a significant reduction in hematopoietic cell contamination at early passages compared to serum-based media. To differentiate the proliferated MSC into different cells types the relevant protocols and differentiation factors should be used.
PowerStem MSC1 basal medium is stable for 2 years and PowerStem MSC1 growth supplements are stable for 12 months when properly stored. PowerStem MSC1 complete medium (basal + supplements) is stable for 1 month when stored in the dark at 2 - 8 °C. We do not recommend using the complete medium beyond one month. Do not freeze complete PowerStem MSC1 medium.
COMPOSITION:
PowerStem MSC1 contains salts, amino acids, trace elements, hormones, growth factors, enriched human proteins and lipids in an optimized formulation.
SUITABILITY:
Serum-free cultivation of human mesenchymal stem cells (hMSC) while maintaining the undifferentiated state and multi-lineage potential.

Storage Temperature: +2°C - +8°C/-20°C

Panserin 801 is a serum-free (animal-derived components < 0.5 % w/v) and defined culture medium (total protein < 0.5 % w/v) for the cultivation of keratinocytes. It selectively supports the growth of human keratinocytes and concurrently prevents the overgrowth with fibroblasts.
COMPOSITION:
The kit (P04-710801K) contains chemically defined MCDB-153 as basal medium ( P04-710801B) and the following supplements:
- Epidermal Growth Factor (EGF)
- Insulin
- Hydrocortisone
- Ethanolamine
- Phosphoethanolamine
- Bovine Pituitary Extract (BPE)
Equivalent to: KBM-Gold Basal Medium, Defined Keratinocyte SFM basal medium, StemLine Keratinocyte Medium SFM

Storage Temperature: -20°C

Panserin 801 is a serum-free (animal-derived components < 0.5 % w/v) and defined culture medium (total protein < 0.5 % w/v) for the cultivation of keratinocytes. It selectively supports the growth of human keratinocytes and concurrently prevents the overgrowth with fibroblasts.
COMPOSITION:
The kit (P04-710801K) contains chemically defined MCDB-153 as basal medium ( P04-710801B) and the following supplements:
- Epidermal Growth Factor (EGF)
- Insulin
- Hydrocortisone
- Ethanolamine
- Phosphoethanolamine
- Bovine Pituitary Extract (BPE)
Equivalent to: KBM-Gold Basal Medium, Defined Keratinocyte SFM basal medium, StemLine Keratinocyte Medium SFM

Storage Temperature: +2°C - +8°C

Panserin 293S is a complete ready to use medium for the serum-free cultivation of HEK293 cells (Human Embryonic Kidney) in suspension culture.
COMPOSITION:
Based on DMEM / F12 medium with additional oligopeptides (hydrolysates < 0.02 % w/v), hormones and trace elements to support expression and cell growth. This product contains only traces of protein (< 0.002 % w/v) and animal derived components (< 0.0003 % w/v).
SUITABILITY:
Panserin 293S is a particularly enriched medium optimized for the growth of HEK293 cells in suspension culture. Due to its defined composition the purification of final products (recombinant proteins, viruses) from the cell culture is more convenient and economic. This product can also be applied to adapt adherent HEK293 cells into suspension.

Storage Temperature: +2°C - +8°C

Panserin 293S is a complete ready to use medium for the serum-free cultivation of HEK293 cells (Human Embryonic Kidney) in suspension culture.
COMPOSITION:
Based on DMEM / F12 medium with additional oligopeptides (hydrolysates < 0.02 % w/v), hormones and trace elements to support expression and cell growth. This product contains only traces of protein (< 0.002 % w/v) and animal derived components (< 0.0003 % w/v).
SUITABILITY:
Panserin 293S is a particularly enriched medium optimized for the growth of HEK293 cells in suspension culture. Due to its defined composition the purification of final products (recombinant proteins, viruses) from the cell culture is more convenient and economic. This product can also be applied to adapt adherent HEK293 cells into suspension.

Storage Temperature: +2°C - +8°C

Panserin 293S is a complete ready to use medium for the serum-free cultivation of HEK293 cells (Human Embryonic Kidney) in suspension culture.
COMPOSITION:
Based on DMEM / F12 medium with additional oligopeptides (hydrolysates < 0.02 % w/v), hormones and trace elements to support expression and cell growth. This product contains only traces of protein (< 0.002 % w/v) and animal derived components (< 0.0003 % w/v).
SUITABILITY:
Panserin 293S is a particularly enriched medium optimized for the growth of HEK293 cells in suspension culture. Due to its defined composition the purification of final products (recombinant proteins, viruses) from the cell culture is more convenient and economic. This product can also be applied to adapt adherent HEK293 cells into suspension.

Storage Temperature: +2°C - +8°C

Panserin 411 is a fully defined, complete ready-to-use medium for the serum-free cultivation of a multitude of adherent and non adherent cells which are Insulin-dependent (e.g. CHO-cells).
COMPOSITION:
Based on Iscove's MEM, trace elements, albumin, cholesterol, soy lipids, vitamins and insulin were added to the medium. It does not contain any growth or attachment factors. Protein and animal-derived components < 0.2 % w/v. Hydrolysates < 0.001 % w/v.
SUITABILITY:
Panserin 411 is a multi-purpose medium suitable for a variety of cells. In Panserin 411 adherent as well as non adherent cells can be cultivated. As the medium contains no growth factors there is a possibility to investigate the effects of specific growth factors added to the cell culture. Panserin 411 does not contain any attachment factors. With some cell types a pre-treatment of the cell culture vessels with gelatine, collagen, poly-D-lysine or fibronectin may support or enable a culture under serum-free conditions. Please note that a coating may be especially important with low seeding densities.

Storage Temperature: +2°C - +8°C

Endopan 300 SL kit is provided with serum substitute (Panexin SL-S, P04-0065S) and supplements in separate sterile packing. This will enable the user to prepare a medium for special applications. For example, VEGF, FGF-2, or other components may be omitted from the complete medium for specific experimental settings.
COMPOSITION:
300 SL kit contains the following components in single packing:
- Basal Medium Endopan 300 SL
- Serum substitute Panexin SL-S
- EGF (human recombinant Epidermal Growth Factor)
- FGF-2 (human recombinant basic Fibroblast Growth Factor)
- VEGF (human recombinant Vascular Endothelial Growth Factor)
- Vitamin C (Ascorbic Acid phosphate)
- R3-IGF-1 (human recombinant Insulin-like Growth Factor)
- GA (Gentamycin/Amphotericin)
- Hydrocortisone
- Heparin

Storage Temperature: +2°C - +8°C

Endopan 300 SL is designed for serum-free culture of endothelial cells directly after isolation. This exclusive product is optimized for the maintenance and expansion of endothelial cells under serum-free culture conditions.

Storage Temperature: +2°C - +8°C

Various cell culture applications are suitable for other animal sera.
APPLICATION:
- Autologous cell culture systems
- Immuno histochemistry
- Immunoblotting
- Immunofluorescence
- Immunoprecipitation
TEST PARAMETER:
- pH
- Osmolality
- Endotoxin
- Total protein
- Hemoglobin
- Mycoplasma
- Sterility

Storage Temperature: -20°C

Sera Low is a specially selected serum with low endotoxin level. The endotoxin level is lower than 1 EU/ml.
ADVANTAGES:
- Low endotoxin level
- Higher safety (viruses, mycoplasma)
- Suitable for a great variety of cells
- Permanent quality control

Storage Temperature: -20°C